Borderlands 2 Home Movies is activated if we speak to Lilith in Sanctuary after The Once and Future Slab mission.

Borderlands 2 The Man Who Would Be Jack is triggered at the end of The Once and Future Slab, when we speak to Roland in Sanctuary. We have the means to defeat the first two security systems, but Roland has no idea how to get past the third one, because that one requires Jacks presence.

Borderlands 2 Opportunity is a Hyperion city built on an island, and it represents Handsome Jacks most valued thing. Although it may be accessed at an earlier point in the game, it is recommended to first travel here during The Man Who Would Be Jack story mission, for the fact that we will also have…

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Borderlands 2 Hyperion Contract #873 is a mission acquired if we go visit the bounty board from The Highlands area after The Man Who Would Be Jack story mission.

Borderlands 2 The Bane is an optional mission available to us after completing The Once and Future Slab.

When we talk to Rocko in Thousand Cuts at the end of Rockos Modern Strife, we can activate an optional mission called Borderlands 2 Defend Slab Tower.

Talking to Brick in Sanctuary after The Once and Future Slab will grant us the possibility to acquire an optional mission known as Borderlands 2 Rockos Modern Strife.

Borderlands 2 Shoot This Guy in the Face mission can be activated during our first trip to Thousand Cuts. To trigger Borderlands 2 Shoot This Guy in the Face we have to speak with a NPC named Face McShooty.

Borderlands 2 Poetic License side-mission can be acquired after Wildlife Preservation story mission. In order to activate Borderlands 2 Poetic License, we have to speak to Scooter in Sanctuary. He is writing a poem for a woman named Daisy, and he wants us to help him finishing his love poem, by taking pictures of some…

Borderlands 2 The Once and Future Slab is the next story mission that gets triggered when we speak to Roland in Sanctuary to complete Wildlife Preservation.

Borderlands 2 Thousand Cuts region plays an important role for the games story, because on its highest mountain it is the Control Core Angel, the location in which the AI known as Angel has its servers. Otherwise, it is irrelevant to travel here at an earlier moment than the one when we have a mission…

Borderlands 2 Animal Rights is an optional mission that can be acquired by speaking to Mordecai in Sanctuary, after the completion of Wildlife Preservation.

Borderlands 2 Doctors Orders is an optional mission thats available to us after we finish Bright Lights, Flying City.

At the end of Bright Lights, Flying City, the next story mission, called Borderlands 2 Wildlife Preservation, is activated when we speak to Roland in Sanctuary.